TBM Jacobian Generation


 

Written by Owen Phillips. Email Dr. Katherine Narr if you have any questions. For more information, see the protocols page.

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TBM Jacobian

Tensor based morphometry requires all your study subjects to be registered together so that an atlas can be generated. To download the pipeline TBM_make_jacobians right click the link.

Inputs:

  1. Set MDT/Atlass: This is the 4-step MDT atlas you generated in the previous step.
  2. Set Original Data: These are all the subjects that will be included in the analysis.

Outputs: This pipeline outputs both scaled and unscaled jacobians. Scaled are used most often, however, if you have a data set where subjects vary greatly in brain size (FASD), then unscaled may be useful.

  1. Scaled Jacobians
  2. Scaled images in MDT space: these are useful as a check to ensure the registrations are working correctly.
  3. Unscaled Affine + NL Jacobians: These are the unscaled jacobians.
  4. Unscaled images in MDT space: these are useful as a check to ensure the registrations are working correctly.